911370-07-5

Basic information

• Product Name: Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)-
• CAS NO: 911370-07-5
• Molecular Formula: C14H8ClF2N3O2S
• Molecular Weight: 355.752
• Mol File: 911370-07-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)-(911370-07-5)
• EPA Substance Registry System: Pyrido[2,3-d]pyrimidin-7(8H)-one, 4-chloro-8-(2,6-difluorophenyl)-2-(methylsulfinyl)-(911370-07-5)

Safety Data

• Hazardous Substances Data: 911370-07-5(Hazardous Substances Data)

Upstream product

• 1979-98-2 2,4-dihydroxy-2-methylmercaptopyrimidine (zwitterionic form) 
• 33097-11-9 4,6-dichloro-2-methylsulfanylpyrimidine-5-carboxyaldehyde 
• 5509-65-9 2,6-difluoroaniline 
• 444605-13-4 4-Chloro-6-(2,6-difluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde 
• 911110-48-0 4-chloro-2-methylsulfanyl-8-(2,6-difluoro-phenyl)-8H-pyrido[2,3-d]pyrimidin-7-one 
• 1979-98-2 4,6-dihydroxy-2-methylmercaptopyrimidine 

Downstream Products

• 1115184-19-4 4-chloro-8-(2,6-difluorophenyl)-2-{[2-(dimethylamino)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one 
• 1115184-21-8 8-(2,6-difluorophenyl)-2-hydroxy-4-phenylpyrido[2,3-d]pyrimidin-7(8H)-one 
• 1165940-92-0 C₂₀H₁₃F₂N₃O₂S 
• 911370-58-6 3-[2-{[3-(diethylamino)propyl]amino}-8-(2,6-difluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-benzoic acid 
• 911370-57-5 4-[2-{[3-(diethylamino)propyl]amino}-8-(2,6-difluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-benzoic acid 
• 911370-53-1 3-[2-{[3-(diethylamino)propyl]amino}-8-(2,6-difluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-2-methylbenzoic acid 
• 911370-52-0 GS⁽⁸⁰³⁾K₁₀₆₅A 

Relevant articles and documents

Design and development of arrayable syntheses to accelerate SAR studies of pyridopyrimidinone and pyrimidopyrimidinone

Chemoselectivity of chlorine versus methylthio (-SCH3), methylsulfinyl (-SOCH3), or methylsulfonyl [-S(O)2CH3] in either functionalization or substitution of pyridopyrimidinone and pyrimidopyrimidinone was studi

An improved and highly convergent synthesis of 4-substituted-pyrido[2,3-d]pyrimidin-7-ones

A novel and efficient route to 4-substituted-pyrido[2,3-d]pyrimidin-7-ones is described resulting in arrays of compounds with biological interest.

NOVEL COMPOUNDS

Novel substituted 2,4,8-trisubstituted 8H-pyrido[2,3-d]pyrimidin-7-one containing compounds and compositions, and their use use in therapy as CSBP/RK/p38 kinase inhibitors.