911374-72-6

Basic information

• Product Name: 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester
• Synonyms: 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester
• CAS NO: 911374-72-6
• Molecular Weight: 457.479
• Mol File: 911374-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester(911374-72-6)
• EPA Substance Registry System: 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester(911374-72-6)

Safety Data

• Hazardous Substances Data: 911374-72-6(Hazardous Substances Data)

Upstream product

• 672310-19-9 6-hydroxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester hydrochloride 
• 192329-91-2 4-(4-fluorophenoxy)benzenesulfonyl chloride 

Downstream Products

• 911374-74-8 2-[4-(4-fluoro-phenoxy)-benzenesulfonyl]-6-(2-morpholin-4-yl-ethoxy)-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid methyl ester 

Relevant articles and documents

SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, RELATED PRODUCTION METHOD AND USE AS MEDICINE

The invention concerns compounds of formula (I), wherein: at least one substituent R1, R2 or R3 represents an X-Q-Y group which enhances solubility, as well as the use of said compounds as medicines for preventing and/or treating diseases in which matrix metalloproteinases exhibit an increased activity.