911376-42-6

Basic information

• Product Name: 2-Naphthalenecarboxylic acid, 5-[[trans-4-(1,1-dimethylethyl)cyclohexyl]amino]-5,6,7,8-tetrahydro-, methyl ester
• CAS NO: 911376-42-6
• Molecular Formula: C22H33NO2
• Molecular Weight: 343.51
• Mol File: 911376-42-6.mol

Chemical Properties

• CAS DataBase Reference: 2-Naphthalenecarboxylic acid, 5-[[trans-4-(1,1-dimethylethyl)cyclohexyl]amino]-5,6,7,8-tetrahydro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxylic acid, 5-[[trans-4-(1,1-dimethylethyl)cyclohexyl]amino]-5,6,7,8-tetrahydro-, methyl ester(911376-42-6)
• EPA Substance Registry System: 2-Naphthalenecarboxylic acid, 5-[[trans-4-(1,1-dimethylethyl)cyclohexyl]amino]-5,6,7,8-tetrahydro-, methyl ester(911376-42-6)

Safety Data

• Hazardous Substances Data: 911376-42-6(Hazardous Substances Data)

Upstream product

• 5400-88-4 4-tert-butylcyclohexylamine 
• 144464-66-4 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid methyl ester 
• 144464-64-2 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate 
• 3470-50-6 6-Hydroxy-1-tetralone 

Downstream Products

• 929010-43-5 5-[1-(4-tert-butyl-cyclohexyl)-3-(4-trifluoromethoxy-phenyl)-ureido]-5,6,7,8-tetrahydro-naphthalene-2-carboxylic acid methyl ester 

Relevant articles and documents

Design and synthesis of conformationally constrained tri-substituted ureas as potent antagonists of the human glucagon receptor

A series of conformationally constrained tri-substituted ureas were synthesized, and their potential as glucagon receptor antagonists was evaluated. This effort resulted in the identification of compound 4a, which had a binding IC50 of 4.0 nM a

GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE

Substituted aryl and heteroaryl derivatives are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.