911382-89-3Relevant academic research and scientific papers
Peptide cyclization via ring-closing metathesis: The N-alkenoxy peptide approach
Lawrence, James,Jourdan, Muriel,Vallee, Yannick,Blandin, Veronique
scheme or table, p. 4575 - 4581 (2009/03/12)
The preparation of cyclic hexapeptides from N-hydroxy tripeptides building blocks is described. Introduction of an unsaturated chain on the hydroxamate oxygen followed by fragment coupling leads to N,N′-dialkenoxy hexapeptides that are efficiently cyclize
N-Hydroxy and N-acyloxy peptides: Synthesis and chemical modifications
Lawrence, James,Cointeaux, Laure,Maire, Pascal,Vallee, Yannick,Blandin, Veronique
, p. 3125 - 3141 (2008/03/12)
The preparation of a series of N-hydroxy peptides is described, along with their acylation on the oxygen of the pseudopeptide bond. Nineteen N-acyloxy peptides, first examples of this new class of pseudopeptides, were thus synthesized; they present a range of acyl groups, including N-protected amino acyl groups. Possibilities of elongation for these pseudopeptides were also investigated. The Royal Society of Chemistry 2006.
