911383-64-7

Basic information

• Product Name: d4T-5'-p-bromophenyl ethyl L-alaninyl phosphate
• Synonyms: d4T-5'-p-bromophenyl ethyl L-alaninyl phosphate
• CAS NO: 911383-64-7
• Molecular Weight: 558.323
• Mol File: 911383-64-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: d4T-5'-p-bromophenyl ethyl L-alaninyl phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: d4T-5'-p-bromophenyl ethyl L-alaninyl phosphate(911383-64-7)
• EPA Substance Registry System: d4T-5'-p-bromophenyl ethyl L-alaninyl phosphate(911383-64-7)

Safety Data

• Hazardous Substances Data: 911383-64-7(Hazardous Substances Data)

Upstream product

• 3056-17-5 stavudin 
• 19430-76-3 p-bromophenyl phosphorodichloridate 
• 106-41-2 4-bromo-phenol 

Downstream Products

• 106-41-2 4-bromo-phenol 
• 3056-17-5 stavudin 

Relevant articles and documents

Site-specific enzymatic activation of the anti-HIV agent stampidine

Stampidine (STAMP, DDE-113, HI-113, N-[p-(4-bromophenyl)-2',3'-didehydro- 3'-deoxy-5'-thymidylyl]-L-alanine methyl ester, CAS 217178-62-6) and two stampidine analogs containing ethyl or t-butyl groups were synthesized and their rates of enzymatic activation were compared side-by-side. Enzymes such as lipase, esterase and protease did not hydrolyze the butyl substituted STAMP analog. These experimental results show that the site of attack for the enzymatic hydrolysis of STAMP is the ester side chain of the molecule. ECV · Editto Cantor Verlag.