911433-08-4

Upstream product

• 402-31-3 1,3-bis(trifluoromethyl)benzene 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 911432-90-1 2-((1S,4R)-4-Benzyloxymethyl-1,4-dimethyl-cyclobut-2-enylmethoxymethyl)-1,3-bis-trifluoromethyl-benzene 
• 862374-11-6 2,6-bis(trifluoromethyl)benzyl bromide 

Relevant academic research and scientific papers

Asymmetric total synthesis of (-)-merrilactone A: Use of a bulky protecting group as long-range stereocontrolling element

(Chemical Equation Presented) Designer elegance: The transannular aldol reaction of a cyclooctene diketone is the key step in this total synthesis of the natural enantiomer of merrilactone A (see scheme). The configuration of the two stereocenters generated in the formation of the central bicyclo[3.3.0]octane framework of the natural product was established using a specially designed bulky protecting group.