911461-47-7

Basic information

• Product Name: 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE
• Synonyms: 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE;4,6-DICHLOROPYRIMIDINE-5-CARBOXAMIDE
• CAS NO: 911461-47-7
• Molecular Formula: C5H3Cl2N3O
• Molecular Weight: 192
• Mol File: 911461-47-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 202-204 °C(Solv: isopropanol (67-63-0))
• Boiling Point: 311.9°C at 760 mmHg
• Flash Point: 142.4°C
• Appearance: /
• Density: 1.62g/cm³
• Vapor Pressure: 0.000549mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 12.39±0.50(Predicted)
• CAS DataBase Reference: 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE(911461-47-7)
• EPA Substance Registry System: 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE(911461-47-7)

Safety Data

• Hazardous Substances Data: 911461-47-7(Hazardous Substances Data)

Usage

General Description

4,6-Dichloro-5-pyrimidinecarboxamide is a chemical compound with the molecular formula C4H2Cl2N2O. It is a derivative of pyrimidine and is commonly used in the synthesis of pharmaceuticals and agriculture products. 4,6-DICHLORO-5-PYRIMIDINECARBOXAMIDE is known for its potential as an insecticide and fungicide due to its pesticidal properties. It is also used as an intermediate in the production of various pharmaceuticals and agrochemicals. 4,6-Dichloro-5-pyrimidinecarboxamide is a white solid at room temperature and is soluble in organic solvents. It is important to handle this compound with care as it may be harmful if ingested, inhaled, or comes into contact with skin or eyes.

InChI:InChI=1/C5H3Cl2N3O/c6-3-2(5(8)11)4(7)10-1-9-3/h1H,(H2,8,11)

Upstream product

• 87600-97-3 4,6-dichloropyrimidine-5-carboxylic acid chloride 
• 5305-40-8 2,6-dichloro-pyrimidine carbaldehyde 

Downstream Products

• 5305-45-3 4,6-dichloro-5-cyanopyrimidine 

Relevant articles and documents

Substituted aminopyrimidine compounds and their method and use thereof

The invention relates to a new aminopyrimidine compound and an application thereof as a drug for treating disorder or diseases related to PI3-kinase abnormity in a free form or a pharmaceutically acceptable salt and preparation form. The invention also relates to a pharmaceutical composition which contains the new aminopyrimidine compound and an application of the pharmaceutical composition in treating mammal disorder or diseases and especially treating human disorder or diseases related to the PI3-kinase abnormity, such as treatment of immunity and inflammatory diseases of PI3-kinase regulation which plays a leading role in a leucocyte function and treatment of proliferative diseases which are related to PI3-kinase activity and include but not limited to leukaemia and solid tumor.

TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO

The present invention relates to certain trisubstituted aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.