91147-43-2 Usage
Uses
Used in Pharmaceutical Industry:
N-(4,5-Dihydro-1H-imidazol-2-yl)-6-quinoxalinamine is used as a pharmaceutical agent for the treatment of glaucoma. As an α2-Adrenoceptor agonist, it helps to reduce intraocular pressure, which is a key factor in managing glaucoma and preventing further damage to the optic nerve.
Additionally, due to its structural similarity to Brimonidine, it may also have potential applications in other therapeutic areas where α2-Adrenoceptor agonists are beneficial, such as in the treatment of certain cardiovascular conditions or as a component in drug delivery systems to enhance the efficacy and targeted delivery of other medications. However, further research and development would be required to explore these potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 91147-43-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,1,4 and 7 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 91147-43:
(7*9)+(6*1)+(5*1)+(4*4)+(3*7)+(2*4)+(1*3)=122
122 % 10 = 2
So 91147-43-2 is a valid CAS Registry Number.
91147-43-2Relevant academic research and scientific papers
Preparation method of brimonidine debromination impurity
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Paragraph 0018-0020, (2021/03/24)
The invention discloses a preparation method of a brimonidine debromination impurity. The preparation method comprises the following steps: with 2-(methylthio)-2-imidazoline hydriodide as a raw material, carrying out tert-butyloxycarbonyl protection on 2-(methylthio)-2-imidazoline hydriodide, and subjecting the protected 2-(methylthio)-2-imidazoline hydriodide to reacting with 6-aminoquinoxaline to obtain the impurity. The preparation method of the brimonidine debromination impurity provided by the invention has the advantages that the raw materials are easy to obtain, an environment-friendlyeffect is realized, and operation is easy. The prepared brimonidine debromination impurity provides an important basis for quality and safety evaluation of brimonidine, and has important significancefor improvement of a synthesis process.
