911470-51-4

Basic information

• Product Name: (Z)-(S)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-hex-2-enoic acid methyl ester
• CAS NO: 911470-51-4
• Molecular Weight: 392.452
• Mol File: 911470-51-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(S)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-hex-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(S)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-hex-2-enoic acid methyl ester(911470-51-4)
• EPA Substance Registry System: (Z)-(S)-2-Benzyloxycarbonylamino-4-tert-butoxycarbonylamino-hex-2-enoic acid methyl ester(911470-51-4)

Safety Data

• Hazardous Substances Data: 911470-51-4(Hazardous Substances Data)

Upstream product

• 160801-72-9 (S)-(1-(methyloxy(methyl)amino)-1-oxobutan-2-yl)carbamate tert-butyl ester 
• 34306-42-8 Boc-Abu 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 153371-25-6 (2S)-2-(tert-butoxycarbonyl)aminobutyraldehyde 

Downstream Products

• 911470-84-3 [(1S,3S)-3-(4-Chloro-benzylamino)-1-(piperidine-1-carbonyl)-pentyl]-carbamic acid benzyl ester 

Relevant articles and documents

Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines

In this paper, we report the synthesis of diastereomerically pure N-(4-substituted-2,4-diaminobutanoyl)piperidines. These compounds were prepared to investigate the influence of the 4-substitution on the dipeptidyl peptidase II (DPP II) activity and selectivity of the parent N-(2,4-diaminobutanoyl)piperidine. The (4S)-methyl compound showed subnanomolar inhibition, comparable with the parent compound. The (4R)-methyl group or bigger substituents decreased the activity.