91159-79-4

Usage

Uses

Used in Polymer Synthesis:
4-AZIDOANILINE HYDROCHLORIDE is used as a monomer in the preparation of photo-reactive polymers, specifically poly(acrylic acid) with incorporated phenylazido groups. The presence of the azide group enables the formation of reactive intermediates upon exposure to light, which can be utilized for various applications, such as the development of self-healing materials or controlled drug release systems.
Used in Peptide Synthesis:
4-AZIDOANILINE HYDROCHLORIDE is used as a building block in the synthesis of 1-(4-aminophenyl)-1H-[1,2,3]-triazol-4-ylcarbonyl-Phe-Gly-Phe-Gly-OH, a compound with potential applications in the pharmaceutical industry. The azide group can be used to introduce a triazole ring through click chemistry, which can be further functionalized to create novel bioactive molecules.
Used in Polysaccharide Synthesis:
4-AZIDOANILINE HYDROCHLORIDE is suitable for use in the synthesis of photo-reactive polysaccharides. The incorporation of the azide group into polysaccharide structures allows for the development of new materials with unique properties, such as stimuli-responsive hydrogels or targeted drug delivery systems. The photo-reactivity of the azide group can be exploited to control the cross-linking and degradation of these materials under specific conditions.

Purification Methods

Purify it in EtOAc with dry HCl gas followed by cold dry Et2O. The free base has m 66o(dec) (MeOH) and the picrate has m 64-65o(dec) (MeOH). The IR has max (Nujol) at 2110cm-1 (N3). [Escher et al. Helv Chim Acta 62 1217 1979, Maffei & Rivolta Gazetta Chim Ital 84 750 1954, Beilstein 12 H 772, 12 IV 1741.]

InChI:InChI=1/C6H6N4.ClH/c7-5-1-3-6(4-2-5)9-10-8;/h1-4H,7H2;1H