91159-94-3Relevant academic research and scientific papers
Triazole-substituted nitroarene derivatives: Synthesis, characterization, and energetic studies
Kommu, Nagarjuna,Ghule, Vikas D.,Kumar, A. Sudheer,Sahoo, Akhila K.
, p. 166 - 178 (2014/01/06)
A series of dense and energetic polynitroaryl-1,2,4-triazoles were synthesized through the nitration of aryl-1,2,4-triazoles. The Cu-catalyzed/base-mediated coupling reactions of haloarenes with 1,2,4-triazoles delivered N-aryl-1,2,4-triazoles. These new
One-step conversion of azine N -oxides to α-1,2,4-triazolo-, 1,2,3-triazolo, imidazolo-, and pyrazoloheteroarenes
Keith, John M.
supporting information; experimental part, p. 2722 - 2725 (2010/07/17)
Pyridine, quinoline, isoquinoline, azaindole, and pyrimidine N-oxides were converted to their α-triazole and α-diazole derivatives by treatment with the corresponding p-toluenesulfonylazoles and Hunigs base at elevated temperatures.
Synthesis and cytoprotective antiulcer activity of 2- or 4-(1H-pyrazol- 1-yl)pyrimidine derivatives related to mepirizole and dulcerozine
Ikeda, Masazumi,Maruyama, Kazumi,Nobuhara, Youichi,Yamada, Toshihiro,Okabe, Susumu
, p. 1700 - 1706 (2007/10/03)
(1H-Pyrazol-1-yl)-, (1H-imidazol-1-yl)-, and (1H-1,2,4-triazol-1- yl)pyrimidines were prepared and evaluated for cytoprotective antiulcer activity. Among them, 4-methoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine (18) showed potent inhibition of the HCl-ethanol-induced and water-immersion stress-induced ulcers in rats, as well as low acute toxicity.
