91165-19-4Relevant academic research and scientific papers
THE SYNTHESIS AND CHEMISTRY OF AZOLENINES. PART 8. THE PAAL-KNORR REACTION WITH CYCLIC 2-(ACYLMETHYL)-2-ALKYL-1,3-DIKETONES: ISOLATION OF 1-ACYL-1H-PYRROLES VIA REARRANGEMENT
Maini, Prem Nath,Sammes, Michael P.,Katritzky, Alan R.
, p. 161 - 168 (2007/10/02)
Treatment of cyclic 2-acylmethyl-2-alkyl-1,3-diketones with ammonium acetate under reflux in acetic acid gives moderate to high yields of 1-acyl-1H-pyrroles by rearrangement.Some of the cyclic diketones react quantitatively with liquid ammonia to yield 2-
Synthesis of 1-Acyl-1H-pyrroles from Cyclic 2-(Acylmethyl)-1,3-diketones via Rearrangement involving Transannular Interaction
Sammes, Michael P.,Maini, Prem Nath,Katritzky, Alan R.
, p. 354 - 355 (2007/10/02)
Cyclic 2-(acylmethyl)-1,3-diketones are converted into 1-acyl-1H-pyrroles in high yields by ammonium acetate in acetic acid, via rearrangement of a hydroxypyrroline intermediate.
