911790-35-7

Upstream product

• 37441-50-2 1,4-butanesultam 
• 51839-15-7 5-iodo-isophthalic acid dimethyl ester 

Downstream Products

• 911790-36-8 5-(1,1-dioxo-[1,2]thiazinan-2-yl)isophthalic acid monomethyl ester 
• 1539276-45-3 N-[(1S,2R)-1-benzyl-2-hydroxy-3-(3-methoxybenzylamino)propyl]-5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N',N'-dipropylisophthalamide 
• 1539276-56-6 N-[(1S,2S)-1-benzyl-2-hydroxy-3-(1-methyl-1-phenylethylamino)propyl]-5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N',N'-dipropylisophthalamide 
• 1539276-55-5 N-[(1S,2R)-1-benzyl-2-hydroxy-3-(1-methyl-1-phenylethylamino)propyl]-5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N',N'-dipropylisophthalamide 
• 1539276-54-4 N-{(1S,2S)-1-benzyl-2-hydroxy-3-[1-(3-methoxyphenyl)-1-methylethylamino]propyl}-5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N',N'-dipropylisophthalamide 
• 706803-45-4 N-{(1S,2R)-1-benzyl-2-hydroxy-3-[1-(3-methoxyphenyl)-1-methylethylamino]propyl}-5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N',N'-dipropylisophthalamide 
• 1349180-49-9 5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N,N-dipropylisophthalamic acid 
• 1349188-02-8 5-(1,1-dioxo-[1,2]thiazinan-2-yl)-N,N-dipropylisophthalamic acid methyl ester 

Relevant academic research and scientific papers

BACE-2 INHIBITORY COMPOUNDS AND RELATED METHODS OF USE

Provided herein are novel compounds of Formulae I-III, and methods of using the same to selectively inhibit BACE2.

Substituted 1,2-ethylenediamines, Methods for Preparing Them and Uses Thereof

The present invention relates to substituted 1,2-ethylenediamines of general formula (I) wherein the groups R1 to R15, A, B, L, i as well as X1-X4 are defined as in the specification and claims and the use thereof for the treatment of Alzheimer's disease (AD) and similar diseases.