911850-37-8Relevant articles and documents
Design and synthesis of potential new apoptosis agents: hybrid compounds containing perillyl alcohol and new constrained retinoids
Das, Bhaskar C.,Mahalingam, Sakkarapalayam M.,Panda, Lipsa,Wang, Bo,Campbell, Phillp D.,Evans, Todd
scheme or table, p. 1462 - 1466 (2010/04/29)
Novel retinoids 1-3 containing perillyl alcohol were synthesized through the addition of perillyl alcohol to the activated carboxylic acids (retinoids) promoted by DCC (N,N′-dicyclohexyl carbodiimide). A set of structurally and functionally diverse perillyl alcohol derivatives of retinoids were obtained in good yields (78-82%). Biological evaluation of these novel hybrid compounds (containing retinoids and perillyl alcohol) is currently underway in our laboratory.
A very efficient route toward the 4a-methyltetrahydrofluorene skeleton: short synthesis of (±)-dichroanone and (±)-taiwaniaquinone H
Alvarez-Manzaneda, Enrique,Chahboun, Rachid,Cabrera, Eduardo,Alvarez, Esteban,Alvarez-Manzaneda, Ramón,Meneses, Ricardo,Es-Samti, Hakima,Fernández, Antonio
supporting information; experimental part, p. 3384 - 3388 (2009/09/08)
A very expedient and efficient new route toward taiwaniaquinoids, bearing the 4a-methyltetrahydrofluorene skeleton, is reported. Key steps are the intramolecular Friedel - Crafts alkylation of an aryldiene and the degradative oxidation of a methylenedioxy
