91190-04-4Relevant academic research and scientific papers
HETEROCYCLIZATION OF FUNCTIONALIZED KETENE ACETALS: SYNTHESIS OF PYRIMIDINES VIA VINYLAMIDINE INTERMEDIATES
Shishoo, C. J.,Devani, M. B.,Bhadti, V. S.,Ananthan, S.,Ullas, G. V.
, p. 1291 - 1292 (1984)
Stable N-(carbethoxycyanovinyl)amidines have been isolated from the reaction of benzamidine with carbethoxycyanoketene S,N-acetals and have been found to cyclize to 4-chloro-, 4-amino- and 4-hydroxypyrimidines depending upon the cyclizing agent employed.
Synthesis and Spectroscopy of N-(Cyanovinyl)amidines
Shishoo, Chamanlal J.,Devani, Muljibhai B.,Bhadti, Vishweshwar S.,Ananthan, Subramaniyam,Ullas, Giliyar V.
, p. 3886 - 3897 (2007/10/02)
N-(Cyanovinyl)amidines (3a-k), presumed intermediates in the synthesis of pyrimidines from cyanoketene S,N-acetals and amidines, have been synthesized and characterized.I.r. and 1H n.m.r. studies indicate that these vinylamidines exist, preferentially, in the intramolecularly hydrogen bonded E form (9a).
