91191-94-5

Upstream product

• 63296-56-0 (S)-(benzyloxymethoxy)propanal 
• 3587-60-8 Benzyloxymethyl chloride 
• 122151-35-3 (S)-N,N-dimethyl-2-(benzyloxymethoxy)propionamide 
• 63296-55-9 (S)-(-) ethyl 2-<(benzyloxy)ymethoxy>propanoate 

Downstream Products

• 1222555-65-8 (S)-2-(benzyloxymethoxy)propyl 4-methylbenzenesulfonate 
• 174627-68-0 Trifluoro-methanesulfonic acid (S)-2-benzyloxymethoxy-propyl ester 
• 140886-06-2 ((S)-2-Bromo-1-methyl-ethoxymethoxymethyl)-benzene 
• 63296-56-0 (S)-(benzyloxymethoxy)propanal 
• 137095-91-1 (2S,2'S)-2'-(Benzyloxymethoxy)propyl 3,3,3-trifluoro-2-methoxy-2-phenylpropionate 

Relevant academic research and scientific papers

Enantiotopic group differentiation and kinetic resolution: Asymmetric reduction of meso-1,3-dihalides

Asymmetric reduction of 1,3-dihalides derived from glycerol occurs with moderate levels of enantiotopic group differentiation. A concomitant kinetic resolution increases the enantiometric purity of the initial product.

High Diastereoface Selection in an Ester Enolate Addition to α-Alkoxy Aldehydes: Stereoselective Synthesis of α-Methylene-β-hydroxy-γ-alkoxy Esters

The aldol-type condensation of β-(dimethylamino)propionates 3 and 4 with a series of α-alkoxy aldehydes proceeds with unprecedented high stereoselectivity (up to 24:1) to give anti α-methylene-β-hydroxy-γ-alkoxy esters.The best results were obtained when the reaction was carried out in diethyl ether and the ester enolate was allowed to equilibrate to the thermodynamically more stable geometric isomer.