91202-74-3

Basic information

• Product Name: Carbamic acid, [2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-2-oxoethyl]-, phenylmethyl ester
• CAS NO: 91202-74-3
• Molecular Formula: C14H20N2O6
• Molecular Weight: 312.323
• Mol File: 91202-74-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-2-oxoethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-2-oxoethyl]-, phenylmethyl ester(91202-74-3)
• EPA Substance Registry System: Carbamic acid, [2-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]-2-oxoethyl]-, phenylmethyl ester(91202-74-3)

Safety Data

• Hazardous Substances Data: 91202-74-3(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 
• 159396-61-9 benzyl 2,5-dioxo-oxazolidine-3-carboxylate 

Downstream Products

• 91202-77-6 N^α-benzyloxycarbonyl-N-[tris(β-D-galactopyranosyloxymethyl)methyl]glycinamide 
• 151734-51-9 N-[1,1-bis(hydroxymethyl)-2-acetoxyethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 170124-33-1 5-(O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)hydroxymethyl)-5-(N-(benzyloxycarbonyl)glycinamido)-2-phenyl-1,3-dioxane 
• 170124-35-3 Acetic acid (2R,3S,4S,5R,6R)-3,5-diacetoxy-2-acetoxymethyl-6-[5-(2-amino-acetylamino)-2-phenyl-[1,3]dioxan-5-ylmethoxy]-tetrahydro-pyran-4-yl ester 
• 223930-08-3 (3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-carbamic acid 2-(2-benzyloxycarbonylamino-acetylamino)-3-hydroxy-2-hydroxymethyl-propyl ester 
• 223930-13-0 (3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decyl)-carbamic acid 5-(2-benzyloxycarbonylamino-acetylamino)-2,2-dimethyl-[1,3]dioxan-5-ylmethyl ester 
• 512168-91-1 N-[1-t-butyldiphenylsilyloxymethyl-2-[(1-oxohexadecyl)oxy]-1-[(1-oxohexadecyl)oxymethyl]ethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 512168-85-3 N-[1-acetoxymethyl-2-[(1-oxohexadecyl)oxy]-1-[(1-oxohexadecyl)oxymethyl]ethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 512168-88-6 N-[1-formyloxymethyl-2-[(1-oxohexadecyl)oxy]-1-[(1-oxohexadecyl)oxymethyl]ethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 167986-19-8 N-[1-hydroxymethyl-2-[(1-oxohexadecyl)oxy]-1-[(1-oxohexadecyl)oxymethyl]ethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 511545-34-9 N-(2,2-dimethyl-5-[(1-oxohexadecyl)oxymethyl]-[1,3]dioxan-5-yl)-N^α-(benzyloxycarbonyl)glycinamide 
• 167986-18-7 N-[1,1-bis(hydroxymethyl)-2-[(1-oxohexadecyl)oxy]ethyl]-N^α-(benzyloxycarbonyl)glycinamide 
• 512168-82-0 N-(2,2-dimethyl-5-[(1-oxododecyl)oxymethyl]-[1,3]dioxan-5-yl)-N^α-(benzyloxycarbonyl)glycinamide 
• 512168-89-7 N-(2,2-dimethyl-5-(t-butyldiphenylsilyloxymethyl)-[1,3]dioxan-5-yl)-N^α-(benzyloxycarbonyl)glycinamide 

Relevant articles and documents

A strategy for the targeting of photosensitizers. Synthesis, characterization, and photobiological property of porphyrins bearing glycodendrimeric moieties

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Selective protection strategies in the synthesis of TRIS-fatty ester derivatives

A methodology for the selective synthesis of lipophilic acyl derivatives of the glycinamido triol (1) with either one, two, or three fatty ester groups has been established. Peracylation of (1), with palmitoyl chloride gave the triacylated derivative. Conversion of (1) into the acetonide, followed by acylation with either palmitoyl chloride or lauroyl chloride, and acetal hydrolysis provided the monoacylated derivatives. Treatment of (1) with trimethyl orthoacetate gave the orthoacetate derivative. Mild hydrolysis provided the monoacetate/diol. Acylation of the two hydroxyl groups with palmitoyl chloride gave the dipalmitate/acetate. Selective cleavage of the acetate group afforded the dipalmitate of (1). Analogous chemistry with trimethyl orthoformate provided the same dipalmitate via the orthoformate, monoformate/diol, and dipalmitate/formate. A more robust synthesis of the dipalmitate was achieved by converting the hydroxyl group of the acetonide of (1) into a tert-butyldiphenylsilyl ether, followed by acetal hydrolysis, palmitoylation of the liberated hydroxyl groups, and desilylation.

Vesicles and other supramolecular systems made from double-tailed synthetic glycolipids derived from galactosylated tris(hydroxymethyl)aminomethane

A series of double-tailed hydrocarbon glycolipids derived from tris(hydroxymethyl)aminomethane (Tris) have been prepared. These amphiphiles consist of three parts: a hydrophilic head derived from mono- or polygalactosylated Tris, a linking arm of peptidic