91203-82-6Relevant articles and documents
Development of a QuEChERS-Based Stable-Isotope Dilution LC-MS/MS Method to Quantitate Ferulic Acid and Its Main Microbial and Hepatic Metabolites in Milk
Waterstraat, Martin,Hildebrand, Andreas,Rosler, Margit,Bunzel, Mirko
, p. 8667 - 8677 (2016/11/29)
Forage plants of the Poaceae family are grown as pasturage or used for the production of hay, straw, corn stover, etc. Although ferulic acid contents of grasses are generally high, the amount of ingested ferulic acid differs depending on the type of forage, resulting in varying contents of ferulic acid and its microbial and hepatic metabolites in milk. Concentrations and patterns of these metabolites may be used as markers to track different forages in livestock feeding. Therefore, we developed a stable isotope dilution assay to quantitate ferulic acid, 12 ferulic acid-based metabolites, p-coumaric acid, and cinnamic acid in milk. Because most analytes were not commercially available as stable isotope labeled standard compounds, they were synthesized as 13C- or deuterium-labeled standard compounds. A modification of the QuEChERS method, a Quick, Easy, Cheap, Effective, Rugged, and Safe approach usually applied to analyze pesticides in plant-based products, was used to extract the phenolic acids from milk. Determination was carried out by LC-ESI-MS/MS in scheduled multiple reaction monitoring modus. By using three different milk samples, the applicability of the validated approach was demonstrated.
A selective preparation of highly deuterated hydroxybenzoic acids
Nakamura, Kozo,Morozumi, Kazuki,Amano, Daisuke
scheme or table, p. 332 - 336 (2012/05/31)
A practical method to prepare selected deuterated hydroxybenzoic acids was developed. A hydroxybenzoic acid was dissolved or suspended in deuterium oxide (D2O), then deuterium chloride (DCl) was added to adjust the pD to 0.32, and the mixture w
Synthesis of deuterium-labelled, optically active, ferroelectric liquid crystals
Marini,Domenici,Malanga,Menicagli,Veracini
experimental part, p. 3472 - 3477 (2010/06/17)
The synthesis of two selectively deuterium-labelled 4-(((S)-1-((S)-1-((S)-2-methylbutoxy)-1-oxopropan-2-yloxy)-1-oxopropan-2-yloxy)carbonyl)phenyl 4′-(heptyloxy)biphenyl-4-carboxylate derivatives is reported. A new preparation strategy was developed in or
Study of the ferroelectric liquid crystal 11EB1M7 by means of 2NMR
Catalano, Donata,Chiezzi, Leonardo,Domenici, Valentina,Geppi, Marco,Veracini, Carlo Alberto
, p. 10104 - 10113 (2007/10/03)
In this work, a new procedure for the synthesis of the selectivity deuterium-labeled chiral liquid crystal (+)-(S)-4-[4′-(1-methylheptyloxy)] biphenyl 4(10-undecenylox)benzoate (11EB1M7) has been developed, aimed to the study of its structure, orientational ordering, and dynamic behavior by means of 2H NMR. 11EB1M7 was investigated throughout its mesophasic range, formed by a very rich variety of chiral liquid crystalline phases including blue, cholesteric, TGBA*, and smectic C*. Two isotopomers were synthesized by labeling 11EB1M7 on either the phenyl or the biphenyl moiety of the mesogenic core. This allowed structural information (such as the tilt angle of the rigid fragments of the molecule and the angle between their para axes), orientational order parameters, and individual diffusional coefficients for the various overall and internal motions to be obtained from 2H NMR spectra and relaxation measurements by applying suitable data analyses based on several theoretical models.
Studies on the biosynthesis of the antibiotic reductiomycin in Streptomyces xanthochromogenus
Cho,Beale,Graff,Mocek,Nakagawa,Omura,Floss
, p. 12296 - 12304 (2007/10/02)
The biosynthesis of the antibiotic reductiomycin (1) in Streptomyces xanthochromogenus was investigated by feeding experiments with radioactive and stable isotope-labeled precursors. NMR and mass spectroscopic analyses of the labeled 1 samples revealed th
