91224-37-2

Basic information

• Product Name: D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE
• Synonyms: [D-ARG1,D-TRP7,9,LEU11]-SUBSTANCE P HYDROCHLORIDE;(D-ARG1,D-TRP7,9,LEU11)-SUBSTANCE P;D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2;D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE;H-D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2;(D-arg1,D-trp7,9,leu11)-substance P*acetate;D-ARG1,D-TRP7,9,LEU11]-SUBSTANCE P (SPANTIDE);M.W. 1497.80 C75H108N20O13
• CAS NO: 91224-37-2
• Molecular Formula: C₇₅H₁₀₈N₂₀O₁₃
• Molecular Weight: 1497.81
• Product Categories: Tachykinin receptor
• Mol File: 91224-37-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.43±0.1 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 13.31±0.20(Predicted)
• CAS DataBase Reference: D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE(91224-37-2)
• EPA Substance Registry System: D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE(91224-37-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 91224-37-2(Hazardous Substances Data)

Usage

General Description

D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE is a synthetic peptide chemical compound that consists of a sequence of amino acids. D-ARG-PRO-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-LEU-NH2 HYDROCHLORIDE is often used in research and medical settings for its potential biological and therapeutic activities. It is believed to have capabilities such as inducing protein synthesis, promoting cell growth, and modulating immune responses. Additionally, this compound has shown potential in various fields such as neuroscience, endocrinology, and oncology, making it a subject of interest in the development of new pharmaceuticals and treatments.

InChI:InChI=1/C75H108N20O13/c1-42(2)35-55(64(80)98)89-67(101)56(36-43(3)4)90-69(103)59(39-46-41-85-51-23-11-9-20-48(46)51)93-68(102)57(37-44-17-6-5-7-18-44)91-70(104)58(38-45-40-84-50-22-10-8-19-47(45)50)92-66(100)52(27-29-62(78)96)86-65(99)53(28-30-63(79)97)87-71(105)61-26-16-34-95(61)74(108)54(24-12-13-31-76)88-72(106)60-25-15-33-94(60)73(107)49(77)21-14-32-83-75(81)82/h5-11,17-20,22-23,40-43,49,52-61,84-85H,12-16,21,24-39,76-77H2,1-4H3,(H2,78,96)(H2,79,97)(H2,80,98)(H,86,99)(H,87,105)(H,88,106)(H,89,101)(H,90,103)(H,91,104)(H,92,100)(H,93,102)(H4,81,82,83)/t49-,52?,53+,54+,55+,56?,57+,58-,59-,60?,61?/m1/s1

Upstream product

• 35661-60-0 Fmoc-Leu-OH 
• 71989-31-6 Fmoc-Pro-OH 
• 35661-40-6 N-Fmoc L-Phe 

Relevant articles and documents

TRIPARTITE MODULATORS OF ENDOSOMAL G PROTEIN-COUPLED RECEPTORS

The present invention relates to tripartite compounds comprising a modulator moiety for endosomal G protein-coupled receptors like neurokinin-1 receptor, a linker and a lipid anchor suitable for anchoring the tripartite compound into a plasma membrane. The present invention also relates to a prodrug and a pharmaceutical composition comprising the tripartite compound and the use of the tripartite compound for the treatment of a disease or disorder mediated by endosomal G protein-coupled receptors signalling like NK1R signalling.