912284-75-4

Usage

Type of compound

Ethanol derivative

Attached functional groups

Amino group, Bromine atom

Usage

Organic synthesis, Medicinal chemistry (building block for synthesis of pharmaceuticals and biologically active compounds)

Potential applications

Research and development of new drugs and materials

Structural特点

Suitable for modification and incorporation into various chemical and biological systems

Versatility

Contributed by its structure and potential uses in different fields

Upstream product

• 364-73-8 4-Bromo-1-fluoro-2-nitrobenzene 

Relevant academic research and scientific papers

SYK INHIBITORS

The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)

Preparation of substituted 1,2,3,4-tetrahydroquinoxalines and 2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepines from catalytic Cp*Ir hydrogen transfer N-heterocyclization of anilino alcohols

The [Cp*IrCl2]2/K2CO3 catalyzed hydrogen transfer N-heterocyclization on a series of anilino alcohols has been investigated. The catalyst (20% loading) converts anilino alcohols to 1,2,3,4-tetrahydroquinoxalines and 2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepines in 30-84% isolated yield.