91232-30-3

Usage

Structure

A pyridine derivative with a fluorophenyl group attached to the 2-position and two phenyl groups attached to the 4and 6-positions of the pyridine ring

Appearance

Yellowish to brownish solid

Solubility

Sparingly soluble in water, soluble in organic solvents

Uses

Versatile building block in organic synthesis, studied for potential applications in materials science and pharmaceutical research

Significance

Unique structure and properties make it an intriguing target for further investigation in the field of organic chemistry

Upstream product

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• 618-36-0 rac-methylbenzylamine 

Relevant academic research and scientific papers

Multi-substituted pyridine derivative and its preparation method

The invention discloses a polysubstituted pyridine derivative and a preparation method thereof. The derivative has a structure as shown in specification, wherein R1, R2, R3, R4 and R5 all are any one selected from hydrogen atom, halogen atom, alkyl, aryl, substituted aryl, acyl, amino, nitryl and alkoxy; the invention also discloses a preparation method of the polysubstituted pyridine derivative; the preparation method comprises the following steps: by taking acetyenic ketone and 1-arylethylamine as raw materials, and under the action of appropriate alkali, heating to have a reaction in the solvent to obtain the polysubstituted pyridine derivative as shown in the formula at high yield. The preparation method is mild in reaction condition, short in reaction time, wide in substrate range, high in reaction specifity, high in yield and simple in after-treatment.

Base-Promoted β-C(sp3)-H Functionalization of Enaminones: An Approach to Polysubstituted Pyridines

A convenient one-pot base-promoted synthesis of polysubstituted pyridines from 1-arylethylamines and ynones through the direct β-C(sp3)-H functionalization of enaminones under metal-free conditions has been developed. An intermolecular Michael addition reaction and an intramolecular condensation were involved in this procedure, which features high regioselectivity, high efficiency, and environmental friendliness. Various polysubstituted pyridines were provided in up to 92% yield for 34 examples.

Synthesis of Some New 2,4,6-Triarylpyridines Using Phenacylidenedimethylsulfuranes

Phenacylidenedimethylsulfurane and p-chlorophenacylidenedimethylsulfurane were reacted with α,β-unsaturated ketones in the presence of ammonium acetate in glacial acetic acid to give 2,4,6-triarylpyridines in 45-70percent yields.The structures of the pyri

Pyrylium Compounds. XXI. - Structure and Tautomerism of Pseudobases of Unsymmetrically Substituted 2,4,6-Triarylpyrylium Salts

Hydrolytic ring opening of unsymmetrically substituted 2,4,6-triarylpyrylium salts 11 results in a mixture of two tautomeric pseudobases, the penten-1,5-diones 13 and 14.In crystalline state as a rule one of these tautomers markedly predominates, whereas