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7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is a chemical compound that belongs to the category of organoborons, characterized by the presence of a boron atom within its structure. It is a boronic ester, where the hydroxyl group (OH) of a boronic acid is substituted by an alkoxy group. 7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is distinguished by a methyl group attached to an indole nucleus and a boronic acid pinacol ester group, which contributes to its stability and reactivity. It is widely recognized for its utility in chemical reactions, particularly in Suzuki coupling reactions that facilitate the formation of carbon-carbon bonds, and is commonly employed in the synthesis of complex molecules within chemical and pharmaceutical research.

912331-68-1

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912331-68-1 Usage

Uses

Used in Pharmaceutical Research:
7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is used as a reagent in pharmaceutical research for the synthesis of complex molecules. Its stability and reactivity make it a valuable component in the creation of new pharmaceutical compounds.
Used in Chemical Research:
In chemical research, 7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is used as a key intermediate in the synthesis of various organic compounds. Its role in Suzuki coupling reactions is particularly significant, as these reactions are instrumental in forming carbon-carbon bonds, which are fundamental to the structure of many organic molecules.
Used in Organic Chemistry:
7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is used as a catalyst in organic chemistry, specifically in Suzuki coupling reactions. It aids in the formation of carbon-carbon bonds, which are crucial for constructing the backbones of complex organic molecules.
Used in the Synthesis of Bioactive Compounds:
7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is used as a building block in the synthesis of bioactive compounds. Its unique structure allows for the creation of molecules with potential biological activity, which can be further explored for therapeutic applications.
Used in Material Science:
In material science, 7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER may be used as a component in the development of new materials with specific properties, such as those with enhanced conductivity or stability, due to its reactivity and ability to form stable bonds.
Used in the Development of Advanced Chemical Reactions:
7-METHYL-1H-INDOLE-2-BORONIC ACID PINACOL ESTER is used as a catalyst in the development of advanced chemical reactions that require the formation of carbon-carbon bonds. Its application in these reactions can lead to more efficient and selective synthetic pathways.

Check Digit Verification of cas no

The CAS Registry Mumber 912331-68-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,3,3 and 1 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 912331-68:
(8*9)+(7*1)+(6*2)+(5*3)+(4*3)+(3*1)+(2*6)+(1*8)=141
141 % 10 = 1
So 912331-68-1 is a valid CAS Registry Number.

912331-68-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

1.2 Other means of identification

Product number -
Other names 7-methyl-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-3-yl)-1H-indole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:912331-68-1 SDS

912331-68-1Downstream Products

912331-68-1Relevant academic research and scientific papers

Iridium(I)-Catalyzed C?H Borylation in Air by Using Mechanochemistry

Pang, Yadong,Ishiyama, Tatsuo,Kubota, Koji,Ito, Hajime

supporting information, p. 4654 - 4659 (2019/03/17)

Mechanochemistry has been applied for the first time to an iridium(I)-catalyzed C?H borylation reaction. By using either none or just a catalytic amount of a liquid, the mechanochemical C?H borylation of a series of heteroaromatic compounds proceeded in air to afford the corresponding arylboronates in good-to-excellent yields. A one-pot mechanochemical C?H borylation/Suzuki–Miyaura cross-coupling sequence for the direct synthesis of 2-aryl indole derivatives is also described. The present study constitutes an important milestone towards the development of industrially attractive solvent-free C?H bond functionalization processes in air.

IMIDAZOPYRIDAZINE COMPOUNDS

-

Page/Page column 62, (2008/06/13)

The present invention relates to novel substituted imidazo[1,2-b] pyridazine compounds of Formula (I) pharmaceutical compositions thereof, and the use such compounds as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric disorders and neurological diseases.

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