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7-fluoro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-3-yl)-1H-indole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

912331-75-0

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912331-75-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 912331-75-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,3,3 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 912331-75:
(8*9)+(7*1)+(6*2)+(5*3)+(4*3)+(3*1)+(2*7)+(1*5)=140
140 % 10 = 0
So 912331-75-0 is a valid CAS Registry Number.

912331-75-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole

1.2 Other means of identification

Product number -
Other names 7-FLUORO-2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-INDOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:912331-75-0 SDS

912331-75-0Downstream Products

912331-75-0Relevant academic research and scientific papers

Picolinic acids as β-exosite inhibitors of botulinum neurotoxin A light chain

Bremer, Paul T.,Xue, Song,Janda, Kim D.

supporting information, p. 12521 - 12524 (2016/10/24)

In developing small-molecule inhibitors of botulinum neurotoxin serotype A light chain (BoNT/A LC), substituted picolinic acids were identified. Extensive investigation into the SAR of the picolinic acid scaffold revealed 5-(1-butyl-4-chloro-1H-indol-2-yl)picolinic acid (CBIP), which possessed low micromolar activity against BoNT/A. Kinetic and docking studies demonstrated binding of CBIP to the β-exosite: a largely unexplored site on the LC that holds therapeutic relevance for botulism treatment.

IMIDAZOPYRIDAZINE COMPOUNDS

-

Page/Page column 66, (2008/06/13)

The present invention relates to novel substituted imidazo[1,2-b] pyridazine compounds of Formula (I) pharmaceutical compositions thereof, and the use such compounds as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric disorders and neurological diseases.

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