912341-98-1

Basic information

• Product Name: 2,2,2-trifluoro-N-[1-(4-trifluoromethyl-phenyl)-vinyl]-acetamide
• Synonyms: 2,2,2-trifluoro-N-[1-(4-trifluoromethyl-phenyl)-vinyl]-acetamide
• CAS NO: 912341-98-1
• Molecular Weight: 283.173
• Mol File: 912341-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2,2-trifluoro-N-[1-(4-trifluoromethyl-phenyl)-vinyl]-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-trifluoro-N-[1-(4-trifluoromethyl-phenyl)-vinyl]-acetamide(912341-98-1)
• EPA Substance Registry System: 2,2,2-trifluoro-N-[1-(4-trifluoromethyl-phenyl)-vinyl]-acetamide(912341-98-1)

Safety Data

• Hazardous Substances Data: 912341-98-1(Hazardous Substances Data)

Upstream product

• 709-63-7 1-(4-trifluoromethylphenyl)ethanone 
• 15996-83-5 1-[4-(trifluoromethyl)phenyl]ethanone oxime 
• 407-25-0 trifluoroacetic anhydride 

Relevant articles and documents

Efficient synthesis of chiral phenethylamines: preparation, asymmetric hydrogenation, and mild deprotection of ene-trifluoroacetamides

A mild and efficient route to enantioenriched aryl alkyl amines from ketones has been developed. The first successful synthesis and asymmetric hydrogenation of ene-trifluoroamides from oximes gave highly enantioenriched trifluoroacetamides (94-98% ee). The corresponding phenethyl amides are liberated under mild conditions (K2CO3, MeOH/H2O). In addition, a new application of Josiphos ligands toward the asymmetric hydrogenation of both ene-acetamides and ene-trifluoroacetamides was discovered.