912350-79-9Relevant academic research and scientific papers
Versatile, fragrant, convertible isonitriles
Pirrung, Michael C.,Ghorai, Subir
, p. 11772 - 11773 (2007/10/03)
The metalation of oxazoles leads to ring opening to the isocyanoenolate that can be O-acylated to give the unsaturated isonitriles. These substances undergo conventional multicomponent reactions. The products of their reactions are readily converted to acyl substitution products by treatment with acid and a nucleophile. These unsaturated isonitriles are notable by their simple preparations and, unusually, their nonoffensive odors. Copyright
