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Ethyl8-methoxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-4-carboxylate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

912366-83-7

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912366-83-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 912366-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,3,6 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 912366-83:
(8*9)+(7*1)+(6*2)+(5*3)+(4*6)+(3*6)+(2*8)+(1*3)=167
167 % 10 = 7
So 912366-83-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H17NO4/c1-3-19-14(17)10-6-9-4-5-11(18-2)8-12(9)15-13(16)7-10/h4-5,8,10H,3,6-7H2,1-2H3,(H,15,16)

912366-83-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 8-methoxy-2-oxo-1,3,4,5-tetrahydro-1-benzazepine-4-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:912366-83-7 SDS

912366-83-7Upstream product

912366-83-7Downstream Products

912366-83-7Relevant academic research and scientific papers

Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors

Zhao, Lianyun,Zhang, Yingxin,Dai, Chaoyang,Guzi, Timothy,Wiswell, Derek,Seghezzi, Wolfgang,Parry, David,Fischmann, Thierry,Siddiqui, M. Arshad

scheme or table, p. 7216 - 7221 (2011/01/03)

A novel series of CHK1 inhibitors based on thienopyridine template has been designed and synthesized. These inhibitors maintain critical hydrogen bonding with the hinge and conserved water in the ATP binding site. Several compounds show single digit nanomolar CHK1 activities. Compound 70 shows excellent enzymatic activity of 1 nM.

SUBSTITUTED HETEROCYCLES AND THEIR USE AS CHK1, PDK1 AND PAK INHIBITORS

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Page/Page column 59, (2008/06/13)

This invention relates to novel compounds of Formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds possess CHK1 kinase inhibitory activity, PDK1 inhibitory activity and Pak kinase inhibitory activity and are accordingly useful in the treatment and/or prophylaxis of cancer.

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