912445-05-7 Usage
Uses
ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Potent PARP inhibitor.
Check Digit Verification of cas no
The CAS Registry Mumber 912445-05-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,4,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 912445-05:
(8*9)+(7*1)+(6*2)+(5*4)+(4*4)+(3*5)+(2*0)+(1*5)=147
147 % 10 = 7
So 912445-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H16N4O.2ClH/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12;;/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17);2*1H/t13-;;/m1../s1