912645-77-3Relevant academic research and scientific papers
Synthesis and anticonvulsant activity of 1-formamide-triazolo[4,3-a] quinoline derivatives
Wei, Cheng-Xi,Deng, Xian-Qing,Chai, Kyu-Yun,Sun, Zhi-Gang,Quan, Zhe-Shan
experimental part, p. 655 - 662 (2011/12/01)
Using 6-hydroxy-3,4-dihydro-2(1H)-quinolone as the starting material, a series of 1-formamide-triazolo[4, 3-a]quinoline derivatives (6a-6n) was synthesized, the anticonvulsant effect and neurotoxicity of the compounds was calculated with maximal electrosh
Design, synthesis of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-ones with anticonvulsant activity
Sun, Xian-Yu,Zhang, Lei,Wei, Cheng-Xi,Piao, Hu-Ri,Quan, Zhe-Shan
experimental part, p. 1265 - 1270 (2009/10/02)
A new series of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-one derivatives were synthesized. Their anticonvulsant activities were evaluated by the maximal electroshock (MES) test, and their neurotoxicities were evaluated by the rotarod neurotox
Synthesis and anti-inflammatory activity evaluation of novel 7-alkoxy-1-amino-4,5-dihydro[1,2,4]triazole[4,3-a]quinolines
Sun, Xian-Yu,Wei, Cheng-Xi,Chai, Kyu-Yun,Piao, Hu-Ri,Quan, Zhe-Shan
experimental part, p. 288 - 293 (2009/04/04)
In this study, a novel series of 7-alkoxy-1-amino-4,5-dihydro[1,2,4] triazole[4,3-a]quinolines were synthesized by using 6-hydroxy-3,4-dihydro-2(1H)- quinolone as the starting material. These compounds were evaluated for anti-inflammatory activity through
Anticonvulsant and toxicity evaluation of some 7-alkoxy-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline-1(2H)-ones
Jin, Hong-Guang,Sun, Xian-Yu,Chai, Kyu-Yun,Piao, Hu-Ri,Quan, Zhe-Shan
, p. 6868 - 6873 (2007/10/03)
To further investigate anticonvulsant activity of quinoline derivatives, a series of 7-alkoxy-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinoline-1(2H)-one derivatives was synthesized starting from 7-hydroxyl-3,4-dihydro-2(1H)-quinoline. In initial (phase I) scre
