912653-83-9Relevant academic research and scientific papers
Chiral base mediated transformation of cyclic 1,3-diketones
Butler, Benjamin,Schultz, Thomas,Simpkins, Nigel S.
, p. 3634 - 3636 (2008/09/20)
Treatment of certain 1,3-diketones with a chiral lithium amide base results in the formation of a non-racemic lithium mono-enolate; these intermediates can be transformed directly into chiral hydroxyketone products by reduction with DIBAL-H in high yield and with selectivities of up to 99% ee. The Royal Society of Chemistry 2006.
