91272-26-3

Basic information

• Product Name: 2-phenyl-5,6,7,8,9,10-hexahydrocycloocta[d]pyrimidin-4(3H)-one
• Synonyms: 2-phenyl-5,6,7,8,9,10-hexahydrocycloocta[d]pyrimidin-4(3H)-one
• CAS NO: 91272-26-3
• Molecular Weight: 254.332
• Mol File: 91272-26-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-phenyl-5,6,7,8,9,10-hexahydrocycloocta[d]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-5,6,7,8,9,10-hexahydrocycloocta[d]pyrimidin-4(3H)-one(91272-26-3)
• EPA Substance Registry System: 2-phenyl-5,6,7,8,9,10-hexahydrocycloocta[d]pyrimidin-4(3H)-one(91272-26-3)

Safety Data

• Hazardous Substances Data: 91272-26-3(Hazardous Substances Data)

Upstream product

• 1259296-21-3 2-bromo-1-cyclooctene-1-carboxylic acid 
• 1670-14-0 benzamidine monohydrochloride 
• 4017-56-5 ethyl 2-oxocyclooctane-1-carboxylate 

Relevant articles and documents

Microwave-assisted copper-powder-catalyzed synthesis of pyrimidinones from β-bromo α,β-unsaturated carboxylic acids and amidines

β-Bromo α,β-unsaturated carboxylic acids were coupled and cyclized with amidine hydrochlorides by microwave irradiation in the presence of catalytic amounts of copper powder and a base to give the corresponding pyrimidinones in high yields. Georg Thieme Verlag Stuttgart New York.

SATURATED HETEROCYCLES, XLVI SYNTHESIS OF 2-SUBSTITUTED-5,6-PENTAMETHYLENE-, 5,6-HEXAMETHYLENE- AND 5,6-DECAMETHYLENEPYRIMIDIN-4(3H)-ONES

By the reactions of cycloheptanone-, cyclooctanone- and cyclodecanone-β-carboxylic esters and appropriate alkyl- or substituted aryl- and aralkyl amidines, several 2-substituted-5,6-pentamethylene-, 5,6-hexamethylene- and 5,6-decamethylenepyrimidin-4(3H)-one derivatives have been synthesized for pharmacological tests.