912878-83-2 Usage
Uses
Used in Pharmaceutical Industry:
7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline is used as a precursor in the synthesis of various pharmaceuticals for its potential as a dopamine receptor antagonist. Its unique structure allows for the development of new drugs targeting neurological disorders and pain management.
Used in Agrochemical Industry:
7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline is used as a precursor in the synthesis of agrochemicals, leveraging its chemical properties to create compounds that can be used in pest control and crop protection.
Used in Dye Intermediates:
7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline is used as a dye intermediate, contributing to the development of new dyes with specific color properties and applications in various industries, such as textiles and printing.
Used in Medicinal Chemistry Research:
7-Fluoro-6-nitro-1,2,3,4-tetrahydroisoquinoline is used as a research compound in medicinal chemistry to explore its potential in the development of new drugs with antidepressant and analgesic properties, as demonstrated in animal studies. Its structure provides a foundation for further modification and optimization to enhance its therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 912878-83-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,2,8,7 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 912878-83:
(8*9)+(7*1)+(6*2)+(5*8)+(4*7)+(3*8)+(2*8)+(1*3)=202
202 % 10 = 2
So 912878-83-2 is a valid CAS Registry Number.
912878-83-2Relevant academic research and scientific papers
2,4-disubstituted pyrimidine derivative as well as preparation method and application thereof
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, (2021/01/11)
The invention belongs to the field of chemical medicines, and particularly relates to a 2,4-disubstituted pyrimidine derivative as well as a preparation method and application thereof. The invention provides the 2,4-disubstituted pyrimidine derivative, wh
ALK KINASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF
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, (2017/04/18)
An ALK kinase inhibitor compound as represented by Formula I, pharmaceutical composition containing the compound, and preparation method and use thereof in the preparation of drugs serving as an ALK inhibitor for treating cancer.
The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs
Watson, Nigel S.,Adams, Carl,Belton, David,Brown, David,Burns-Kurtis, Cynthia L.,Chaudry, Laiq,Chan, Chuen,Convery, Máire A.,Davies, David E.,Exall, Anne M.,Harling, John D.,Irvine, Stephanie,Irving, Wendy R.,Kleanthous, Savvas,McLay, Iain M.,Pateman, Anthony J.,Patikis, Angela N.,Roethke, Theresa J.,Senger, Stefan,Stelman, Gary J.,Toomey, John R.,West, Robert I.,Whittaker, Caroline,Zhou, Ping,Young, Robert J.
, p. 1588 - 1592 (2011/05/05)
The discovery and evaluation of potent and long-acting oral sulfonamidopyrrolidin-2-one factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifs are described. Unexpected selectivity issues versus tissue plasminogen activator in the form
