91289-36-0 Usage
Description
2-Quinolinecarboxylic acid, 8-amino-(9CI) is a chemical compound with the molecular formula C10H8N2O2. It is a derivative of quinolinecarboxylic acid, with an amino group attached at the 8th position. 2-Quinolinecarboxylicacid,8-amino-(9CI) may have potential applications in various fields, particularly in the pharmaceutical industry, due to its antimalarial and antitumor activities as an aminoquinoline derivative. However, further research is required to fully understand its biological activities and potential uses.
Uses
Used in Pharmaceutical Industry:
2-Quinolinecarboxylic acid, 8-amino-(9CI) is used as a pharmaceutical compound for its potential antimalarial and antitumor activities. Its aminoquinoline structure contributes to these therapeutic properties, making it a candidate for further research and development in the treatment of various diseases.
Used in Scientific Research:
2-Quinolinecarboxylic acid, 8-amino-(9CI) is used as a subject of scientific research to explore its full range of biological activities and potential applications. This includes investigating its interactions with biological systems, understanding its mechanism of action, and identifying any additional therapeutic uses.
Used in Industrial Applications:
While specific industrial applications have not been detailed, 2-Quinolinecarboxylic acid, 8-amino-(9CI) may have potential uses in various industries. Further investigation and experimentation are necessary to determine its specific properties and how they can be applied in different settings.
Check Digit Verification of cas no
The CAS Registry Mumber 91289-36-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,2,8 and 9 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 91289-36:
(7*9)+(6*1)+(5*2)+(4*8)+(3*9)+(2*3)+(1*6)=150
150 % 10 = 0
So 91289-36-0 is a valid CAS Registry Number.
91289-36-0Relevant articles and documents
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Roth,Erlenmeyer
, p. 1064,1067 (1954)
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The Metal-ion-promoted Water- and Hydroxide-ion-catalysed Hydrolysis of Amides
Przystas, Theodore J.,Fife, Thomas H.
, p. 393 - 399 (2007/10/02)
Rate constants have been determined for the hydrolysis of 8-trifluoroacetamidoquinoline-2-carboxylic acid and N-(6-carboxypicolinyl)-2,4-dinitroaniline in water at 70 deg C.The hydrolysis reactions of these amides in the absence of metal ions are OH- catalysed at pH values >7.Divalent metal ions (Co2+, Ni2+, and Zn2+) have a significant catalytic effect on the rates of hydrolysis.Binding of the metal ions to the amides is strong, and saturation occurs at low metal ion concentrations (-1).At saturating concentrations of the metal ions kobs ispH independent at pH- catalysed reactions are not observed.In contrast, the Ni2+ catalysed hydrolysis of the β-lactam, N-(8-quinolyl)azetidin-2-one, proceeds through a metal-ion-promoted OH- reaction.A 0.01 mol dm-1 concentration of Ni2+ (non saturating) provides a rate enhancement of 105 over that observed in the absence of metal ion.The tye of metal ion catalysis observed in amide hydrolysis, i.e., pH independent or OH- dependent, must be determined by the nature of the rate-determining step and the ease of C-N bond breaking.A metal-ion-promoted OH- catalysed reaction will occur att pH values near neutrality when C-N bond breakng is facile and nucleophilic attack is rate determining, whereas when C-N bond breaking is difficult, and therefore part of the rate-determing step, the reaction will be pH independent because of the requirement for protonation of the nitrogen leaving group.
