912940-80-8Relevant academic research and scientific papers
2-Amino-N-pyrimidin-4-ylacetamides as A2A receptor antagonists: 1. Structure-activity relationships and optimization of heterocyclic substituents
Slee, Deborah H.,Chen, Yongsheng,Zhang, Xiaohu,Moorjani, Manisha,Lanier, Marion C.,Lin, Emily,Rueter, Jaimie K.,Williams, John P.,Lechner, Sandra M.,Markison, Stacy,Malany, Siobhan,Santos, Mark,Gross, Raymond S.,Jalali, Kayvon,Sai, Yang,Zuo, Zhiyang,Yang, Chun,Castro-Palomino, Julio C.,Crespo, María I.,Prat, Maria,Gual, Silvia,Díaz, José-Luis,Saunders, John
, p. 1719 - 1729 (2008)
Previously we have described a novel series of potent and selective A 2A receptor antagonists (e.g., 1) with excellent aqueous solubility.1 While these compounds are efficacious A2A antagonists in vivo, the presence of an
