912967-40-9Relevant academic research and scientific papers
Stereoselective synthesis of 2,4,5-trisubstituted tetrahydropyrans using an intramolecular allylation strategy
Jervis, Peter J.,Kariuki, Benson M.,Cox, Liam R.
, p. 4649 - 4652 (2007/10/03)
A highly stereoselective route to 2,4,5-trisubstituted tetrahydropyrans is reported. The key step employs an intramolecular allylation of a (Z)-allylsilane onto an aldehyde under Bronsted acid activation. Complete 1,4-stereoinduction accounts for the form
