912969-50-7

Basic information

• Product Name: (3S,4R)-1-benzyl-4-vinylpyrrolidin-3-ol
• Synonyms: (3S,4R)-1-benzyl-4-vinylpyrrolidin-3-ol
• CAS NO: 912969-50-7
• Molecular Weight: 203.284
• Mol File: 912969-50-7.mol

Chemical Properties

• CAS DataBase Reference: (3S,4R)-1-benzyl-4-vinylpyrrolidin-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-1-benzyl-4-vinylpyrrolidin-3-ol(912969-50-7)
• EPA Substance Registry System: (3S,4R)-1-benzyl-4-vinylpyrrolidin-3-ol(912969-50-7)

Safety Data

• Hazardous Substances Data: 912969-50-7(Hazardous Substances Data)

Upstream product

• 912969-49-4 (3S,4R)-3-(1-benzyl-4-vinyl-pyrrolidin-3-yl) 2,2,4,4-tetramethyl-1,3-oxazolidine-3-carboxylate 

Relevant articles and documents

Asymmetric synthesis of 3-hydroxy-pyrrolidines via tin-lithium exchange and cyclization

We report a method for the synthesis of chiral pyrrolidines using tin-lithium exchange and cyclization reactions. The precursors are formed readily from simple starting materials and undergo tin-lithium exchange by treatment with n-butyllithium. Subsequent intramolecular carbolithiation is stereoselective to give highly enantiomerically enriched pyrrolidines in excellent yields.