912971-30-3Relevant academic research and scientific papers
Benzo[d]imidazole inhibitors of Coactivator Associated Arginine Methyltransferase 1 (CARM1)-Hit to Lead studies
Wan, Honghe,Huynh, Tram,Pang, Suhong,Geng, Jieping,Vaccaro, Wayne,Poss, Michael A.,Trainor, George L.,Lorenzi, Matthew V.,Gottardis, Marco,Jayaraman, Lata,Purandare, Ashok V.
scheme or table, p. 5063 - 5066 (2010/03/31)
Hit to Lead optimization and SAR development led to the identification of the potent and selective benzo[d]imidazole inhibitor (17b) of Co-activator Associated Arginine Methyltransferase (CARM1).
HETEROCYCLIC INHIBITORS OF PROTEIN ARGININE METHYL TRANSFERASES
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Page/Page column 21, (2010/11/24)
A compound of formula I, or a stereoisomer, a tautomer, a pharmaceutically acceptable salt or solvate thereof, methods of using such compounds in the treatment of hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases; and to pharmaceutical compositions containing such compounds
