91323-17-0Relevant academic research and scientific papers
Synthesis and structure of 2-amino-5-azolyl-3-cyano-4H-pyrans
Samet,Shestopalov,Struchkova,Nesterov,Struchkov,Semenov
, p. 1945 - 1951 (2007/10/03)
Previously unknown 5-azolylpyrans were obtained by reactions of N-acetonyl- and N-phenacylimidazoles, -triazoles, and -tetrazoles with arylmethylenemalononitriles. The structure of 2-amino-3-cyano-6-methyl-5-(5-nitrotetrazol-2-yl)-4-phenyl-4H-pyran was es
Azoles. 34. Nitroimidazole derivatives and their antibacterial and fungicidal action
Zaprutko,Wrzeciono,Gajdzinski,Bartkowiak,Lutomski,Michalska,Pietkiewicz
, p. 258 - 261 (2007/10/02)
Nitroimidazole derivatives 4a-4c, 5a-5c, 8a-8c and 9a-9c were synthesized by treating 4,5-dinitro- and 2-methyl-4,5-dinitroimidazole (1,2) or their silver salts [1.Ag,, 2.Ag) with chlorosubtituted phenacyl bromides 3a-3c, diethyl sulphate or ethyl iodide, allyl iodide and ethyl chloro-, azo- or bromoacetate. 2,4(5)-dinitroimidazole (10) has been converted to the 2,4-dinitroimidazole derivative 10a by the action of ethyl bromoacetate in the presence of sodium ethylate. A modified method for the synthesis of 6a and 6b has been described. 7a and 7b have been obtained by a known method. Some of the newly synthesized nitroimidazole derivatives show antibacterial and fungicidal activity.
