913263-04-4 Usage
Uses
Used in Biological Sample Analysis:
(Difluoro-trimethylsilanyl-methyl)-phosphonic acid is used as a pH indicator for assessing the near-neutral pH of biological samples. Its ability to interact with the biological environment and provide a measure of pH is crucial for understanding the physiological conditions and maintaining the stability of the samples during analysis and research. This application is particularly important in fields such as biochemistry, molecular biology, and medical diagnostics, where accurate pH measurements are essential for the proper interpretation of experimental results and the development of effective therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 913263-04-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,3,2,6 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 913263-04:
(8*9)+(7*1)+(6*3)+(5*2)+(4*6)+(3*3)+(2*0)+(1*4)=144
144 % 10 = 4
So 913263-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H11F2O3PSi/c1-11(2,3)4(5,6)10(7,8)9/h1-3H3,(H2,7,8,9)
913263-04-4Relevant academic research and scientific papers
Reily, Michael D.,Robosky, Lora C.,Manning, Matthew L.,Butler, Andrew,Baker, John David,Winters, R. Thomas
, p. 12360 - 12361 (2006)
A new NMR chemical shift standard and pH indicator, difluorotrimethylsilanylphosphonic acid (DFTMP), is described, and the utility of this reagent is demonstrated for in situ determination of pH in complex biofluids. The pH dependence of this reagent allows accurate in situ determination of aqueous solution pH to within an RMSE of 0.02 pH units over a pH range of 5 to 8. Advantages of this reagent over previously described pH-sensitive components include (1) lack of metal binding affinity, (2) minimal disturbance of endogenous spectral regions, and (3) the potential to function as a multinuclear pH indicator and chemical shift reference point for 19F, 1H, and 31P nuclei. This reagent will be generally useful for NMR experiments on biological systems where the pH needs to be accurately measured at the moment of data acquisition. Copyright
