91327-64-9

Upstream product

• 91312-55-9 ethyl (3R/S,5S)-3-O-(tert-butyldimethylsilyl)-5,6-O-isopropylidene-3,5,6-trihydroxyhexanoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 91312-53-7 ethyl (3R/S,5S)-5,6-O-isopropylidene-3,5,6-trihydroxyhexanoate 
• 91312-57-1 (3R/S,5S)-3-O-(tert-butyldimethylsilyl)-3,5,6-trihydroxyhexanoic acid δ-lactone 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

Bakers' yeast oxidation of methyl para-tolylsulfide: Synthesis of a chiral intermediate in the preparation of the mevinic acid-type hypocholestemic agents

The use of (R)-methyl-para-tolylsulfoxide as a chiral auxiliary in a novel synthesis of a key intermediate en route to mevinic acid-type hypocholestemic agents is described. The synthesis is short and simple consisting of eight steps to yield enantiomeric