913288-73-0

Upstream product

• 1088697-26-0 (1'S,2S,2'R,3S)-S-[2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl] 2-benzyloxy-3-hydroxy-3-phenyl-thiopropionate 
• 913288-76-3 (1'S,2'R)-2'-(N-mesitylenesulfonylamino)-1'-phenylpropyl thiolbenzoate 
• 913288-75-2 (2R,3R)-2-methyl-3-phenyl-1-(N-mesitylenesulfonylamino)-aziridine 
• 913288-77-4 (1'S,2'R)-2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl thiolbenzoate 
• 187324-62-5 (1S,2R)-2-(N-mesitylenesulfonylamino)-1-phenylpropan-1-ol 
• 37577-28-9 (1S,2R)-(+)-norphedrine 
• 773-64-8 2-mesitylenesulphonyl chloride 
• 913288-74-1 (1S,2R)-2-(N-mesitylenesulfonylamino)-1-phenyl-1-chloropropane 

Downstream Products

• 1088697-03-3 (1'S,2'R)-S-[2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl] 2-benzyloxy-thioacetate 
• 1088697-38-4 (1'S,2'R)-S-[2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl] 2-(tert-butyl(diphenyl)silyloxy)-thioacetate 
• 1088696-99-4 (1'S,2'R)-S-[2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl] 2-methoxy-thioacetate 
• 913288-94-5 (2S,3R)-3-Benzo[1,3]dioxol-5-yl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-thiopropionic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-91-2 (2S,3R)-3-(tert-Butyl-dimethyl-silanyloxy)-2,4-dimethyl-pent-4-enethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-84-3 (2S,3R)-3-Benzo[1,3]dioxol-5-yl-3-hydroxy-2-methyl-thiopropionic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-93-4 (2S,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2,5-dimethyl-hexanethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-90-1 (2S,3S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-pent-4-enethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-80-9 2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl (1'S,2S,2'R,3S)-2,4-dimethyl-3-hydroxy-thiolpent-4-enoate 
• 913288-82-1 (2S,3S)-3-Hydroxy-2,5-dimethyl-hexanethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-79-6 (2S,3S)-3-Hydroxy-2-methyl-pent-4-enethioic acid S-{(1S,2R)-2-[benzyl-(2,4,6-trimethyl-benzenesulfonyl)-amino]-1-phenyl-propyl} ester 
• 913288-81-0 2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl (1'S,2S,2'R,3S)-2,4-dimethyl-3-hydroxy-thiolpentanoate 
• 913288-78-5 (1'S,2'R)-2'-(N-benzyl-N-mesitylenesulfonylamino)-1'-phenylpropyl thiolpropionate 

Relevant academic research and scientific papers

Anti and syn glycolate aldol reactions with a readily displaced thiol auxiliary

(Chemical Equation Presented) The TBDPS protected glycolate derivative of thiol auxiliary 1 is readily prepared (3 steps, 80% overall yield) and has been shown to give excellent anti:syn selectivity (>97:3) and high facial selectivity (88:12 to 97:3) in g

Achieving high selectivity and facile displacement with a new thiol auxiliary for boron-mediated aldol reactions

(Chemical Equation Presented) Synthesis of a new thiol auxiliary (1) is readily achieved (in five or six steps, >74% overall yield from norephedrine) and is shown to give high diastereoselectivity in boron-mediated anti-aldol reactions with a range of aldehydes. This new thiol auxiliary may be directly displaced by a range of nucleophiles under very mild conditions, to give the corresponding phosphonate esters, alcohols, acids, SNAC thiolesters, and methyl esters.