913719-86-5

Upstream product

• 78-82-0 Isobutyronitrile 
• 1489-53-8 1,2,3-trifluorobenzene 
• 865-47-4 potassium tert-butylate 
• 55553-85-0 potassium 2,2-dimethyl-1-propanolate 
• 145689-34-5 2-(2,3-difluorophenyl)acetonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 1035261-32-5 2-(2-fluoro-3-hydroxyphenyl)-2-methylpropanoic acid 
• 1035261-36-9 2-(2,3-difluorophenyl)-2-methylpropanoic acid 
• 1035261-37-0 diethyl 2-(2-(2,3-difluorophenyl)-2-methylpropanoyl)malonate 
• 1040860-66-9 C₁₀H₉ClF₂O 
• 1040860-64-7 C₁₀H₁₀ClFO₂ 
• 913720-03-3 2-(2,3-difluorophenyl)isobutyramide 
• 913720-04-4 2-(2,6-difluorophenyl)isobutyramide 

Relevant academic research and scientific papers

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.

Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles

Methods for preparing oxindole and thio-oxindole compounds are provided, which compounds are useful as precursors to useful pharmaceutical compounds. Specifically provided are methods for preparing 5-pyrrole-3,3-oxindole compounds and 5-(7-fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile. Also provided are methods for preparing iminobenzo[b]thiophene and benzo[b]thiophenone compounds.