913814-44-5Relevant articles and documents
Total synthesis of (+)-aculeatin D and (+)-6-epi-aculeatin D
Yadav,Raghavendra Rao,Ravindar,Subba Reddy
scheme or table, p. 51 - 54 (2010/07/10)
The stereoselective total synthesis of spiroketal natural product (+)-aculeatin D and unnatural (+)-6-epi-aculeatin D has been accomplished. Sharpless kinetic resolution of secondary allylic alcohol and phenyliodine(III) bis(trifluoroacetate) (PIFA)-mediated oxidative spirocyclization were used as key steps in this synthesis. Georg Thieme Verlag Stuttgart.
Enantioselective synthesis and absolute configurations of aculeatins A, B, D, and 6-epi-aculeatin D
álvarez-Bercedo, Paula,Falomir, Eva,Carda, Miguel,Marco
, p. 9641 - 9649 (2007/10/03)
The three naturally occurring, bioactive spiroacetals aculeatins A, B, and D, as well as the non-natural 6-epi-aculeatin D have been synthesized for the first time in enantiopure form using an asymmetric allylation as the only chirality source. A further