914-16-9

Upstream product

• 108-89-4 picoline 
• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 872-85-5 pyridine-4-carbaldehyde 

Relevant academic research and scientific papers

Iodine-Promoted Synthesis of Dipyrazolo/Diuracil-Fused Pyridines and o-Amino Diheteroaryl ketones via Oxidative Domino Annulation of 2/4-Methylazaarenes

The iodine-promoted oxidative domino annulation and carbonylation process has been developed for the synthesis of biologically important azaarene-substituted bis-pyrazolo[3,4-b:4′,3′-e]pyridines (BPPs), diuracilpyridines and o-amino diheteroaryl ketones. The domino procedure proceeded with easily available methyl azaarenes, 5-aminouracils and substituted 5-aminopyrazoles. This protocol is a simple and metal-free approach which exhibits high functional group compatibility and broad substrates scope. Moreover, this transformation can be applied for the preparation of dipyrazolo/diuracil-fused pyridines on a gram scale. (Figure presented.).

Solvent-free microwave synthesis of bis-pyrazolo[3,4-b:4′,3′-e] pyridines and study of their antifungal properties

The synthesis of a series of bis-pyrazolo[3,4-b:4′,3′-e] pyridines (3) in the reaction of 5-amino-3-methyl-1-phenylpyrazole (1) with aldehydes (2) under microwave irradiation and solvent-free conditions is described. The structure elucidation of the produ