914090-61-2

Upstream product

• 2396-84-1 (2E,4E)-ethyl hexa-2,4-dienoate 
• 112-53-8 1-dodecyl alcohol 
• 251958-12-0 Methanesulfonic acid (R)-1-((R)-5-oxo-tetrahydro-furan-2-yl)-ethyl ester 
• 914090-56-5 5-benzyloxycarbonylamino-4-hydroxyhexanoic acid ethyl ester 
• 914090-58-7 (4R,5R)-ethyl 4,5-dihydroxyhexanoate 
• 914090-60-1 5-(1-azidoethyl)-dihydrofuran-2-one 
• 914090-59-8 5-(1-iodoethyl)-dihydrofuran-2-one 
• 143-15-7 1-dodecylbromide 
• 914090-57-6 5-benzyloxycarbonylamino-4-(tert-butyldimethylsilanyloxy)-hex-2-enoic acid ethyl ester 
• 143289-01-4 (4R,5R,E)-ethyl 4,5-dihydroxyhex-2-enoate 
• 130609-14-2 (R)-5-((R)-1-hydroxyethyl)dihydrofuran-2(3H)-one 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 914090-62-3 (2-hydroxy-1-methyl-5-oxo-heptadecyl)-carbamic acid benzyl ester 

Relevant academic research and scientific papers

An asymmetric aminohydroxylation route to cis-2,6-disubstituted piperidine-3-ol: application to the synthesis of (-)-deoxocassine

A highly efficient, flexible, and convergent route to cis-2,3,6-trisubstituted piperidines has been developed employing the Sharpless asymmetric aminohydroxylation and stereoselective reductive amination by catalytic hydrogenation as the key steps. Its usage is illustrated by the short synthesis of the piperidine-3-ol alkaloid, (-)-deoxocassine.