914202-49-6Relevant articles and documents
Aryl alkyl ketones in a one-pot Gewald synthesis of 2-aminothiophenes
Tormyshev, Victor M.,Trukhin, Dmitry V.,Rogozhnikova, Olga Yu.,Mikhalina, Tatiana V.,Troitskaya, Tatiana I.,Flinn, Anthony
, p. 2559 - 2564 (2008/09/16)
2-Aminothiophene-3-carboxylates bearing various aryl groups at the 4-position are readily obtained in good to moderate yields by the one-pot Gewald reaction of aryl alkyl ketones with ethyl cyanoacetate and elemental sulfur in the presence of morpholinium acetate and excess morpholine. Georg Thieme Verlag Stuttgart.