914222-80-3Relevant articles and documents
Efficient synthesis of tyrosine-derived marine sponge metabolites via acylation of amines with a coumarin
Harburn, J. Jonathan,Rath, Nigam P.,Spilling, Christopher D.
, p. 6398 - 6403 (2005)
Condensation of N-acetylglycine with aldehyde 15 in acetic anhydride gave acetamido coumarin 16. Hydrolysis to the enol coumarin 17 and reaction with hydroxylamine gave the oximino coumarin 18. Reaction of the oximino coumarin 18 with a range of nucleophi