914259-49-7

Basic information

• Product Name: (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-oxo-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester
• Synonyms: (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-oxo-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester
• CAS NO: 914259-49-7
• Molecular Weight: 829.971
• Mol File: 914259-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-oxo-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-oxo-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester(914259-49-7)
• EPA Substance Registry System: (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-oxo-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester(914259-49-7)

Safety Data

• Hazardous Substances Data: 914259-49-7(Hazardous Substances Data)

Upstream product

• 337904-92-4 5-[(tert-butoxycarbonyl)amino]nicotinic acid 
• 914259-46-4 (3R,5S)-3-amino-5-({9-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-9H-xanthen-9-ylmethyl}-carbamoyl)-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 914260-21-2 5-tert-butoxycarbonylamino-1-piperidine-3-carboxylate ammonium salt 
• 914261-15-7 C-{9-[4-(tert-butyl-dimethyl-silanyloxy)-butyl]-9H-xanthen-9-yl}-methylamine 
• 920296-45-3 (3S*,5R*)-5-tert-butoxycarbonylamino-piperidine-1,3-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl)ester 
• 914259-48-6 (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-hydroxy-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 

Downstream Products

• 914259-51-1 (3S,5R)-3-{[9-(3-carboxy-propyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-5-(3,4-dimethoxy-benzenesulfonylamino)-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 914259-52-2 (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(3-dimethylcarbamoyl-propyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 
• 914259-50-0 (3R,5S)-3-(3,4-dimethoxy-benzenesulfonylamino)-5-{[9-(4-morpholin-4-yl-butyl)-9H-xanthen-9-ylmethyl]-carbamoyl}-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester 

Relevant articles and documents

3 -M0N0- AND 3 , 5-DISUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS

The invention relates to 3,5-piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (= disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5- piperidine compound, and/or a method of treatment comprising administering a 3,5- piperidine compound, a method for the manufacture of a 3,5-piperidine compound, and novel intermediates and partial steps for their synthesis. Especially, the 3,5-piperidine compounds have the formula I, wherein the symbols have the meanings described in the specification.