91430-01-2

Upstream product

• 10387-24-3 N-butyl-4-methylaniline 
• 57049-30-6 N-butyl-N-methyl-4-methylaniline 
• 106-49-0 p-toluidine 

Downstream Products

• 861519-40-6 N-butyl-4-methyl-2,6-dinitro-N-nitroso-aniline 
• 861367-23-9 N-butyl-4-methyl-2,6,N-trinitro-aniline 
• 10387-24-3 N-butyl-4-methylaniline 

Relevant academic research and scientific papers

Highly selective sp3 C-N bond activation of tertiary anilines modulated by steric and thermodynamic factors

A highly selective sp3 C-N cleavage of tertiary anilines was achieved using the TBN/TEMPO catalyst system. When N,N-diaklylanilines (alkyl, benzyl) were employed, the N-CH3 bond was selectively cleaved via radical C-H activation. Moreover, when the allyl group was installed, totally reverse selectivity was observed. It is worth noting that the solvent effect is also crucial to obtain high reaction efficiency and selectivity.