91430-24-9

Upstream product

• 5203-14-5 4-butoxybenzonitrile 

Downstream Products

• 478488-89-0 3-(4-Butoxy-phenyl)-5-(3-chloro-thiophen-2-yl)-[1,2,4]-oxadiazole 
• 1428739-10-9 3-(4-butoxyphenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole 

Relevant academic research and scientific papers

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.