91430-26-1

Basic information

• Product Name: 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE
• Synonyms: 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE;AKOS BBB/180
• CAS NO: 91430-26-1
• Molecular Formula: C₁₁H₁₆N₂O₂
• Molecular Weight: 208.26
• Mol File: 91430-26-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.091g/cm³
• Refractive Index: 1.533
• CAS DataBase Reference: 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE(91430-26-1)
• EPA Substance Registry System: 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE(91430-26-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 91430-26-1(Hazardous Substances Data)

Usage

General Description

4-Isobutoxy-benzoic acid hydrazide is a chemical compound with the molecular formula C12H18N2O3. It is a hydrazide derivative of benzoic acid and isobutanol. 4-ISOBUTOXY-BENZOIC ACID HYDRAZIDE is used in the synthesis of pharmaceuticals, agrochemicals, and organic compounds. It has been shown to exhibit anti-inflammatory and anti-tumor properties, making it a potential candidate for drug development. It is also used as a reagent in organic chemistry reactions, particularly in the formation of hydrazones and other derivatives. Additionally, it is known for its ability to chelate metal ions, making it useful in various industrial applications.

InChI:InChI=1/C11H16N2O2/c1-8(2)7-15-10-5-3-9(4-6-10)11(14)13-12/h3-6,8H,7,12H2,1-2H3,(H,13,14)

Upstream product

• 124403-90-3 methyl 4-(2-methylpropoxy)benzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 

Relevant articles and documents

Synthesis, Antiproliferative and Antioxidant Activity of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogues

Two series of 3-mercapto-1,2,4-triazole derivatives containing alkoxy substituents different in size and position were synthesized and their structures were characterized by FT-IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. The synthesized compounds were assessed for their antiproliferative activity against colon cancer cell line (SW480). The results indicated that the size and position of the alkoxy group significantly influenced the antiproliferative activity. The highest cancer cell growth inhibition values were observed for the compounds containing 3,4,5-trimethoxyphenyl groups in their structures (57.74, 54.14 and 60.70% at 50 μM for compounds 5a, 12b and 14, respectively). The synthesized compounds were also subjected to DPPH protocol for evaluating the antioxidant activity. The results showed that all compounds had moderate to high levels of antioxidant capacity as compared to ascorbic acid as standard, the highest free radical scavenging capacity of 75% was observed for compound 4a at 50 μM.